Letrozole 2.5mg

ACTIVE HALF-LIFE: 2 DAYS
CLASSIFICATION: NON-STEROIDAL AROMATASE INHIBITOR
DOSAGE: 0.5 – 2.5 MG/DAY
ACNE: NO
WATER RETENTION: NO
HBR: NO
HEPATOXITY: NO
AROMATIZATION: NO

Letrozole, produced by Ultima Pharmaceuticals, is an anti-estrogen drug that is widely recognized in both medical and athletic fields. Medically, it is mainly used to treat estrogen-related cancers, particularly breast cancer in women. In sports, it helps alleviate the negative effects of estrogenic steroids, such as water retention and gynecomastia in men, among other issues.

This medication is a non-steroidal aromatase inhibitor, with Letrozole as its active ingredient. It has been authorized for human use and is notable for being non-steroidal, non-androgenic, non-toxic to the liver, and free from narcotic or addictive properties.

Made by Bouwen, Letrozole works by inhibiting aromatase, an enzyme essential for estrogen production. Its action mechanism entails obstructing the cytochrome P450 genomic component within aromatase, leading to a significant reduction in estrogen activity—by 75-95% from baseline—after prolonged use.

As part of the latest generation of aromatase inhibitors, Letrozole is similar to Anastrozole but differs from Clomid and Nolvadex, as it directly affects estrogen production rather than merely blocking estrogen receptors.

It is important to highlight that Letrozole from Bouwen is relatively safe when followed as directed, resulting in few side effects. Yet, if misused or in susceptible individuals, there could be complications affecting the digestive, central nervous, respiratory, and musculoskeletal systems, with symptomatic treatment typically employed for any overdose.

The drug is administered orally, irrespective of meals, and is rapidly and completely absorbed by the gastrointestinal tract, achieving a bioavailability of up to 99%, unaffected by food.

The suggested dosage of Letrozole varies from 0.25 to 5 mg daily, tailored to individual needs and tolerance levels. Usage can follow one of two patterns: either as a preventive measure before starting a cycle of estrogenic steroids to prevent complications, or as a continued measure throughout the steroid cycle to manage estrogen-related issues.

Letrozole is effective in preventing side effects associated with estrogen, like water retention, increased body fat, and gynecomastia in men.

Prior to starting Ultima-Femara, it’s essential to review potential risks with a healthcare professional while excluding contraindications such as pregnancy, breastfeeding, reproductive age endocrine conditions, substance intolerances, hypersensitivity to ingredients, and suitability for children.

Certain precautions should also be taken regarding glucose-galactose malabsorption and lactase deficiencies, which may require careful consideration. Generally, dose adjustments are not needed for this medication.

Keep Letrozole out of the reach of children. It is intended for adult use only.