Cardarine (GW-50156)

ACTIVE HALF-LIFE: 20 – 24 Hours
CLASSIFICATION: PPARS AGONIST
DOSAGE: 15mg/Pill
ACNE: NO
WATER RETENTION: NO
HBR: NO
HEPATOXITY: NO
AROMATIZATION: NO

Although frequently categorized as a SARM, cardarine (GW 501516) is actually classified as a PPAR-delta agonist (peroxisome proliferator-activated receptors). It is often marketed in the same way a tomato, which is botanically a fruit, is sold as a vegetable. Cardarine was first identified in the early 1990s through joint efforts between GSK and Ligand Pharma and began phase 1 trials in 2000 to target lipid issues, although these were halted in 2008. Today, it is primarily a research compound and is used by athletes to enhance performance and promote fat loss.

Originally developed to address obesity, diabetes, lipid issues, and heart health, cardarine has shown effectiveness in improving lipid profiles and significantly enhancing cholesterol levels.

Athletes from various disciplines use cardarine to boost endurance. Endurance athletes often combine it with the AMP analog AICAR or use it alone to prolong their training sessions, enabling them to maintain higher intensities without early fatigue. For bodybuilders, cardarine offers the advantages of fat loss along with enhanced workout endurance, which translates into more intense and longer training sessions.

Cardarine was misused by athletes in the lead-up to the 2008 Beijing Olympics and was subsequently banned by WADA in 2009, classifying it as a ‘hormone and metabolic modulator.’ Several cyclists, including Valery Kaykov and Miguel Ubeto, faced repercussions for its use.

Cardarine has been shown to reverse metabolic disturbances in obese and pre-diabetic individuals by stimulating fatty acid oxidation. It promotes fat burning without lowering blood sugar levels, proving effective against obesity.

Cardarine can be combined with other substances for various objectives such as endurance, fat loss, anabolic steroid cycles, during post-cycle therapy (PCT), or linked in a triple stack of SARMs for recomp purposes.

Side effects from cardarine are infrequent, but adhering to the correct dosage and cycling is important. Since it does not influence hormone levels, there is no requirement for PCT or concerns about hormonal suppression.

The recommended dosage for both men and women is 20 mg per day, with a half-life of 20-24 hours. Users may take the entire dose before exercising or split it between the morning and evening. Cardarine is typically taken orally, often followed by juice or water.